BinaxNOW COVID-19 Antigen Self Test from Abbott can be used to detect active infection, with or without symptoms. *>~vclT Walgreens had plenty of the two-test packs, and I heard they were hard to find. 1391 0 obj <> endobj Due to product restrictions, please Sign In to purchase or view availability for this product. This Covid-19 test is easy to use and can provide results in as little as 15 minutes. NOTE: The boxes come 40 tests per box and 16 boxes per case. Bottle that contains 7.5 ml of extraction reagent. We self-funded our entire investment in both test development and manufacturing capacity scale up. How will people report their test results? BinaxNOW COVID-19 Antigen Card Test Specs: 1) How long should people wait between taking BinaxNOW Antigen Tests? We will not share your information for any other purposes. 3) What do I do if my antigen self-test result is invalid from my BinaxNOW COVID Test Bulk? The Abbott BinaxNow Covid-19 POC Test comes equipped with Covid-19 testing steps and all required Covid-19 test supplies. 2 0 obj This kit is designed for anterior nasal samples, which should be taken by a medical professional. BinaxNOWTM COVID-19 Antigen Self Test, COVID Test With 15-Minute Results Without Sending to a Lab, Easy to Use at Home, FDA Emergency Use Authorization. Please check back soon. 424 2nd Ave W, Suite 700 Seattle, WA 98119. The lots of card components, shown in the photos in The New York Times article (143608R and 143467R), were at seven-month shelf life and were disposed of in accordance with our standard inventory management process. When The New York Times contacted us, they told us their story was about how private industry stepped up to fill an important role during the pandemic to develop tests. ZSeFRVF))0#x/@$gYY#+W9r1rP.fiTuDQ+~(tt gG0?Pt(u 2bgC3&ab%ld= #FeV!oM2G3A! endstream endobj startxref WebThe Abbott BinaxNOW Covid-19 POC Antigen Test is a point-of-care test that can help detect the presence of the Covid-19 virus for medical professionals and CLIA certified We've always said that vaccines are the most effective tool we have to combat COVID-19, but they can't do it alone and testing is a critical companion. Please contact Any requests to return products after 14 days from receipt will be denied. The website that you have requested also may not be optimized for your screen size. through email. For EMS, FRO, hospital and law enforcement agencies inTSA-C or D, please email Toby Harbuck at THarbuck@ncttrac.org in TSA-D or Shane Comer at SComer@ncttrac.org in TSA-C. 2. hXmO9+B-UH Insert sample swab into BOTTOM HOLEand firmly push upwards so that the swab tip is visible in the TOP HOLE. The antigen-based test kit contains all of the components needed to test for traces of SARS-CoV-2. 5) How accurate is Abbott's BinaxNOW COVID-19 test? prepaid return label. The next step was a little trickier. dRX1)_ 0uy'9@G{vS&5Sd>&ip6(8Ax BYsV[_>.XV`lFucZn0.f0-%e"M]isL:]l>}whEwieyi5AG: C? Insert sample or control swab into BOTTOM HOLE and rmly push upwards so that the swab tip is visible in the TOP HOLE. Each kit box contains 2 test cards, 2 nasal swabs and 2 reagent bottles. order. 2. A colleague told me they were capped at one test kit when ordering online from Walgreens. ***, ***If your request is for 2,500 COVID-19 test kits or less please continue below.***. You will have 14 business days to drop off your product at the We have not destroyed any finished BinaxNOW product, nor have we destroyed any usable test components needed by the market that could have been donated. Similarly, a single purple or pink control line at the windows top section shows the absence of Covid-19 antigens. endobj Correct x8 Wrong 2. It's important that ongoing guidance and practice recognize the critical role that testing will have in the months ahead. Since then, rapid antigen tests have become more widespread. Two pink/purple-colored lines will appear on a positive specimen, indicating that the Covid-19 antigen has been found. Most of our products ship out within 24-48 business hours, depending on NCTTRAC is distributing free COVID-19 test kits to EMS, FRO, hospital, and law enforcement agencies in TSA-C, D, and E. TO RECEIVE FREE COVID-19 TEST KITS, AGENCIES MUST COMMIT TO COMPLETING THE FOLLOWING REQUIREMENTS: STEP ONE: Register your agency as a Test Site by completing the attached TxRapidTest New Site Request spreadsheet and send it to support@txrapidtest.org Your agency will be notified once their registration is complete. Features. I had never taken a rapid test before, but the instructions were easy to follow. 2020 12 14 Test Coordinator Responsibilities, 2020 12 14 Test Administrator Responsibilities, Medical Waste Instructions for Schools_Final, EMS Workforce Recruitment & Retention Program, Public Education/Injury Prevention Subcommittee, System Performance Improvement Subcommittee. I had to drop some reagent liquid in the correct hole on the test card. Since the onset of this pandemic, no company has made as many tests, as affordably, as Abbott. Open the reagent bottle (or disposable dropper) and apply the fluid to the TOP HOLE on the righthand side of the opened test card. It's important that ongoing guidance and Q: For the This 15 minute program explains how to use the test and how to use the txrapidtest.org web app to register each employee and track their testing.. ***It is critical to this program of free testing that everyone who gets tested MUST be logged into the App for accurate testing counts. unless the product arrived damaged (please review damage products policy ]Z 1432 0 obj <>stream COVID-19 Ag CARD . Abbott BinaxNOW Covid-19 Antigen Card Test (POC), Dentist-Only Halyard Gloves Sale- CLICK HERE for $.06 Gloves When You Buy 2 Cases, INDICAID Point of Care (POC) COVID-19 Rapid Antigen Test, iHealth COVID-19 Antigen Rapid Test (OTC), Flowflex COVID-19 At Home Antigen Test (OTC), Vanguard 3.5 mil Nitrile Exam Gloves, Powder Free, Vanguard Latex Exam Gloves, 5.5 mil, Powder Free, Cream, Demetech DemeMask ASTM Level 3 Surgical Mask with Horizontal Ties, Demetech N95 Surgical Respirator, Cup Style with Headbands, Demetech N95 Surgical Respirator, Fold Style with Headbands, Prevail Incontinence Pads, Chux Pads, Large 23" x 36", Level 2, Non-Sterile Disposable Isolation Gowns, Level 3, Non-Sterile, Disposable Isolation Gowns, Level 3, Sterile, Disposable Isolation Gowns, Cardinal Health Personal Cleansing Cloth Wipe Dimethicone, Non-Flush, Fragrance Free, 9 x 13 in, Cardinal Health Personal Cleansing Cloth Wipe, Fragrance Free, Flushable, 9 x 13 in, Cardinal Health Sure Care Plus Protective Underwear, Heavy Absorbency, Large, Apollo's Perine Foaming Perineal Body Wash 7oz Bottle, PURELL Advanced Hand Sanitizer Gel, 2 Liter Pump Bottle, Aurelia Blush Nitrile Powder Free Examination Gloves, Vanguard 6mil Powder-Free Nitrile Exam Gloves, The control line is blue and not pink/purple, There is a pink/purple line by sample, but no line by control, The control line is blue, but the sample is pink/purple, Ensure that your Purchase Order correctly reflects the order placed on Note: For BinaxNOW swab controls, hold the extraction reagent vertically above the top hole and slowly add eight drops on the swabs top opening. McKesson Acceptable Dating: we will ship >= 90 days. DO NOT touch the card with the dropper tip while dispensing. Claim: Dark colors on at home test strip shows COVID is in the water { support@bttnusa.com with your order Thank you for confirming your email. x=]6UIw; \qMxk}G*ci\n|d@7Fyn]~qsZ? In May, as vaccinations climbed and summer arrived, demand for testing plummeted, and public health guidelines told vaccinated people to refrain from testing unless they had symptoms. The nasal swabs should be tested as soon as possible. Abbott is providing these links to you only as a convenience, and the inclusion of any link does not imply endorsement of the linked site by Abbott. shipping policy page. As a result, the site may contain information on pharmaceuticals, medical devices and other products or uses of those products that are not approved in other countries or regions. But they don't detect the virus with as much sensitivity as PCR tests, so there's a greater chance of getting a false negative. Designed and Powered by Amplus Agency - Copyright 2023 - All rights reserved. endstream endobj 1392 0 obj <>/Metadata 130 0 R/Outlines 183 0 R/Pages 1387 0 R/StructTreeRoot 206 0 R/Type/Catalog>> endobj 1393 0 obj <>>>/Rotate 0/StructParents 0/Tabs/S/Type/Page>> endobj 1394 0 obj <>stream 2 X 8.8 mL. If not, put the swabs in a clean, unused plastic container labeled with patient information at room temperature. BinaxNOW COVID-19 Antigen Card has built-in procedural controls. WebThe BinaxNOW COVID-19 Antigen Self Test is only for use under the Food and Drug Administrations Emergency Use Authorization. Customers are Abbott can also work with retailers to prioritize distribution to areas of the country where the virus is surging as additional supply comes online. [y6``j*j}dmKS?% >xN!A'J;hce)3+XWn{+ These swabs provide one with a record of the overall test. They wanted to know how we navigated the changing public health guidance and public behaviors. drop-shipped (product status is 7-14 Days) directly from the manufacturer We appreciate your feedback. However, it will be replaced by a pink/purple line, indicating that the sample has flowed through the test strip the reagents are functioning. This rapid-result test is for personal use. The Abbott BinaxNOW Covid-19 POC Antigen Test is a point-of-care test that can help detect the presence of the Covid-19 virus for medical professionals and CLIA certified businesses. This test is authorized for use at the Point of Care (POC), i.e., inpatient care settings operating under a CLIA Certificate of Waiver, Certificate of Compliance, or Certificate of Accreditation. 0 Can I use this test to meet travel requirements for testing? According to studies, Abbotts BinaxNOW COVID Test Bulk antigen self-test has an accuracy rate of 84.6% for detecting covid-19 infections, and 98.5% for correctly identifying covid-19 negatives. Repeat the same procedure in the second nostril. If you are paying by check, please promptly send all checks to A |4JPpC, sx`~4 nEm >n3Ci (BH1:4 .GpqE50"v[g 0>b3vO7TtA`a !IDyope>=^opv; eA` Gw; Ys}T~S%0N qP:pN iC];G7@o-9:b"$%?2&u}G@R , &K!XA2A=s;]#O=Apadj|"S >H7 ! This test is offered by eMed, please visit www.emed.com for further information. Hold the extraction reagent vertically above the top hole and slowly add six drops on the swabs top opening. I'm glad the directions included a diagram for this step. Abbott has always worked in the best interests of public health through this pandemic and will continue to do so. WebQ: How many tests can be completed with one bottle of reagent? Procedure for BinaxNOW Swab Controls Open the test card just prior to use, lay it flat, and perform assay as follows. Easily perform this COVID-19 test with a simple nasal swab in the comfort and convenience of your own home. Our administrators will review your account and you will receive an email with login instructions upon approval, prompting you to set a password. less than 90-day shelf life), outdated, or seasonal product qualifies for a return based on the above guidelines. Following step one in the instructions, I washed my hands before getting started. The product will be inspected for quality assurance upon delivery and a refund issued it can take up to 7-10 business days to reflect on your original form Make sure you use 6 DROPS of reagent Additionally, if a photo is not BinaxNOW is the leading rapid test because it's reliable, easy to use and detects COVID-19 and all of its variant strains. Free Shipping on Orders Over $35. 2 ct box . If testing at more than one location, you will support@bttnusa.com In the email, Rapid antigen tests are convenient, but they're not as sensitive as PCR tests. SIMPLE AND EASY TO USE: The BinaxNOW Self Test from Abbott requires just a shallow nasal swab that you can do yourself; includes easy-to-follow instructions, SEE RESULTS IN 15 MINUTES: Convenient, fast results anytime, anywhere; no need for a prescription or sending to a lab, #1 COVID-19 SELF TEST IN THE US: BinaxNOW Self Test uses the same technology used by doctors. Unless otherwise specified, all product and service names appearing in this Internet site are trademarks owned by or licensed to Abbott, its subsidiaries or affiliates. @K~H3v33eR(p(th)c(A:UpW,~k4)R)yuBEaYu&B67A=7Emfgu?G2GnD'N.,6+:us{7MqRFt *N'@yRy* GY=6\R]Q]|?bnO]q1uMRyo}QWu&OdZ|_}. WebHold Extraction Reagent bottle vertically. reason for returning, and attach any applicable pictures. DO NOT touch the card with the dropper tip while dispensing. <> 2) How do I know if I have a positive or negative test? It has been authorized by the FDA under an Emergency Use Authorization. For symptomatic use, a single test can be used. of receiving your order. DO NOT touch the card with the dropper tip while dispensing. If your order qualifies for a return label (products that are damaged or %%EOF Carefully read instructions prior to starting test. Hold Extraction Reagent bottle vertically. For proof of negative COVID-19 test, the BinaxNOW COVID-19 Ag Card Home Test may be a better choice, OPTIONAL SELF-REPORT: Capture your results in the NAVICA app for self reporting. binaxnow covid-19 card rapid antigen test, SPH SC-ET-HD Portable Electrostatic Sprayer, 40 sterile, single swabs for specimen sampling. Links which take you out of Abbott worldwide websites are not under the control of Abbott, and Abbott is not responsible for the contents of any such site or any further links from such site. Our comprehensive portfolio of Safe Patient Handling solutions includes replacement single patient use Air Transfer Mattresses, Overhead Patient Lifts, Mobile Lifts, a complete line of SPU Slings,Infection Prevention solutionsand Strategic Sourcing for critical healthcare supplies. The FDA highlighted a study that found that the BinaxNOW COVID-19 test kit was 91.7% accurate at detecting positive cases and 100% reliable at finding negative Please inspect your order upon receipt and contact bttn immediately if your ?9QeO7.""j&qt2: Ic&CH|EC41 =aGN_[sb=BEh'*#ON 4 0 obj you will be issued a refund to your original form of payment. above) or you received the wrong product. Its important to remember that each COVID-19 Ag card must be used once only and cannot be reused. number to request a cancellation. Abbott respects the quality and dating requirements of countries in the same manner as we do in the U.S. Abbott manufactures another high-quality rapid test, Panbio, which is also affordable and approved in most countries outside the U.S. We have been able to supply all international orders for that product. 3 0 obj The kit was pretty well-designed for minimizing human error on this step: I removed the swab at the stick end, and inserted the soft tip into my nostril. Even a faint line next to the word "sample" on the BinaxNOW COVID-19 test card is a positive result. Each box has 40 tests, but only ONE reagent bottle so you cannot split a box between multiple locations. Abbott's Response to The New York Times Article. Nucleocapsid protein antigen from SARS-CoV-2, Cardboard kit box with individually foiled wrapped test cards, 40 cardboard, book-shaped hinged test cards with test strips, 1 x 7.5 mL extraction reagent bottle with reagent, 40 sterile nasal swabs, 1 positive control swab containing non-infectious recombinant SARS-CoV-2 nucleocapsid antigen, 1 negative control swab, 1 product insert, 1 procedure card, Electrophoresis, Western Blotting and ELISA, Chromatography and Mass Spectrometry Reagents, Laboratory Syringe Needles and Accessories, Lab Coats, Aprons, and Other Safety Apparel, Sharps Disposal Containers and Accessories, Classroom Laboratory Supplies and Consumables, Applied Biosystems TaqMan Assay and Arrays Search Tool, Applied Biosystems TaqMan Custom Assay Design Tools, Applied Biosystems Custom qPCR Primers and TaqMan Probes Tool, Chemical Storage and Management Resource Center, Cost-effective, high performing test designed for decentralized testing, Simple test procedure using direct nasal swab, Onboard extraction allows swab to be directly inserted into test card, 40 cardboard, book-shaped hinged test cards with test strips, 1 x 7.5 mL extraction reagent bottle with reagent, Non-infectious recombinant SARS-CoV-2 nucleocapsid antigen, Emergency Use Authorization (EUA) supports testing in patient care settings operating under a CLIA Certificate of Waiver, Certificate of Compliance, or Certificate of Accreditation. The chemicals vary among kits and companies, but sodium azide is the most common chemical, the center said. WebProcedure for BinaxNOW Swab Controls Open the test card just prior to use, lay it flat, and perform assay as follows. WebStep 1: Add the extraction reagent to the BinaxNOW COVID-19 Ag Card by holding the bottle vertically (NOT at an angle), hovering inch above the TOP HOLE, slowly adding eight (8) drops. Learn More. Make sure they are dry before starting. My test card was identical to the negative result diagram, with a single pink line where it said "control." 3. In fact, because Abbott maintained usable test components, we're now able to scale up. bttn offers a variety of shipping options to best fit your orders. With a total of 40 cards and 7.5 mL of extraction reagent included in the kit, it provides a significant amount of flexibility in analyzing multiple samples. 4. Easy to use 15 min. In good laboratory practice, positive and negative controls are recommended to check if the reagents are functional and the test is done appropriately. In order to check for a positive result, you will need to look at the result window for two pink (or purple) lines. NOTE: The boxes come 40 tests per box and 16 boxes per case. If your test comes back positive, you may be infected with COVID-19. Currently, the minimum acceptable dating for our COVID lateral flow tests is nine months or about 80% of shelf life in most countries outside of the U.S. Governments do not accept short-dated product, even when donated, because of the time it takes to get through their networks. Product Type : Once the refund has been STEP TWO: Identify your agencys Test Administrator by having that individual go to preparingtexas.org/ and complete the BinaxNOW Training Module (Binax 200). WebProduct Dating. Covid-19 testing will be critical if people have to resume their everyday lives. This COVID-19 test can be used for people with and without symptoms. ]>~\a_]-_?UYuLfjgyVZ52hgoXQm]}FmfUG}Obw0`ZZ9LES aJ0u%+,hPKUqUUUU)%~YURL}Un:hW8%&0_,x^QUUskWma_J6CB'g,/eLM9ac-v~"ff" 8{X'sQL&nJ-|PX)$m2Z%=OE9GKcb~~X- 'Jm9$~\>|O+=Ob>0ona/}/luM35[fG!1@N;Jpn\Wn8= }ggi }OFk0cAxEtz'&Yv <>>> ABBOTT'S RESPONSE TO THE NEW YORK TIMES ARTICLE. <> Fisher Scientific is always working to improve our content for you. 1 0 obj I tried my best to use enough of the solution, but the dropper spit out several air bubbles along with it. availability. UNSPSC Code. 263a, that meet the requirements to perform moderate, high, or waived complexity tests. 1416 0 obj <>/Filter/FlateDecode/ID[<7A596AB39F42C5418088222AF06F93F8><898B4C630ACCA844A084361655AAA848>]/Index[1391 42]/Info 1390 0 R/Length 119/Prev 554430/Root 1392 0 R/Size 1433/Type/XRef/W[1 3 1]>>stream After 15 minutes, one should be able to read the findings. WebBinaxNOW COVID-19 Antigen Self Test from Abbott can be used to detect active infection, with or without symptoms. If you wish to cancel your order, you must request a discomfort, bruising and or broken skin on the bridge of the nose. stream It detects multiple strains, including the DELTA and OMICRON variants, DESIGNED TO DETECT ACTIVE COVID-19 INFECTION: Includes 2 tests designed to detect active infection with or without symptoms. ,!*N`yJ>Y9\r`pR|Qd{Dc%EV8MRO#7mA=O:R7rhKQhs-jQ;p7nlq]Vth-,wk(I d40I 0&-2@(dpT q 9 iq @( {x,f eaa1acnbfgY. `;J+|n00d1_@s : g Z8JA1 WebBinaxNOW Product Demo Library. CVS allows four tests per customer in stores, or six per purchase online. If your product is eligible for return contact If testing at more than one location, you will need to order an appropriate number of boxes. But, the resulting story implied that disposing of short-dated test components was the wrong thing to do; when, in fact, we took the best actions based on quality standards and the rapidly changing environment. WebThe BinaxNOW COVID-19 Ag Card is an immunochromatographic membrane assay that uses highly sensitiveantibodies to detect SARS-CoV-2 nucleocapsid protein from nasal swab specimens. The site owner may have set restrictions that prevent you from accessing the site. WebBinaxNOW COVID-19 Card Rapid Antigen Test also comes with two disposable swabs to be used as negative and positive controls for the test strips. responsible for the shipping costs associated with returning the product, Close and seal the card. BinaxNOW COVID-19 Card Rapid Antigen Test also comes with two disposable swabs to be used as negative and positive controls for the test strips. information on our shipping policy, please refer to our It would have taken months to complete manufacturing, create individualized regulatory filings in countries, obtain regulatory approvals, ship product overseas in exact specified storage conditions, and then get it to the people who need ittoo late for the product to be widely used. WebBinaxNOW COVID-19 Reagent Safety Data Sheet This document has been prepared in accordance with the SDS requirements of the OSHA Hazard Communication Standard I trusted the gold-standard test wouldn't steer me wrong, especially if I quarantined before taking it. COVID-19 Antigen tests are commonly used in the diagnosis of respiratory pathogens, including influenza viruses and respiratory syncytial virus. After that, proceed to follow instructions 2-4 of the specimen test procedure. Correct Hold Extraction Reagent bottle vertically. was delivered. With a total of 40 cards and DO NOT touch the card with the dropper tip while dispensing. of payment. If your product is damaged, you Web1. The website you have requested also may not be optimized for your specific screen size. endobj <>/ExtGState<>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/Annots[ 22 0 R] /MediaBox[ 0 0 612 792] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> WebBinaxNow COVID-19 Antigen Self Test . The BinaxNOW test is not approved outside the U.S. Funders and most governments have very specific shelf-life requirements. For a documented test result the BinaxNOW COVID-19 Ag Card Home Test may be a better choice. 1. shipped before cancellation is confirmed, you will not be able to cancel your bttn will only accept returns up to 14 business days after your delivery date. endstream endobj 2273 0 obj <>/Filter/FlateDecode/Index[117 2142]/Length 66/Size 2259/Type/XRef/W[1 1 1]>>stream Before closing the card, I made sure to turn the swab to the right three times to mix my sample with the reagent drops. After your cancellation has been confirmed, You do not have access to stopandshop.com. Requested URL: stopandshop.com/groceries/health-beauty/diabetic-home-health-care/at-home-tests-monitoring/binaxnow-covid-19-antigen-self-test-2-ct-box.html, User-Agent: Mozilla/5.0 (Macintosh; Intel Mac OS X 10_15_7) AppleWebKit/537.36 (KHTML, like Gecko) Chrome/92.0.4515.159 Safari/537.36. Please be aware that the website you have requested is intended for the residents of a particular country or region, as noted on that site. The package contains positive and negative control sterilized swabs. rapid antigen test for detecting active infections of COVID-19. Combined with the NAVICA App and with a negative result, you will have a digital result that may meet travel requirements. BinaxNOW COVID-19 Reagent The processes of testing have now been made easier and faster with this improved testing technique. At that time, Abbott had significant amounts of finished test kits in inventory to supply expected demand. Hold Extraction Reagent bottle vertically Hovering 1/2 BinaxNOW. A rapid test for the qualitative detection of Covid-19 antigens in nasal swab specimens. I slid the snotty swab tip though the two holes in the test card as instructed. We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. The U.S.'s first over-the-counter rapid COVID-19 test kits Abbott's BinaxNOW Self Test and Ellume's COVID-19 Home Testare being sold at Walmart, The Covid-19 rapid test kit is used for detecting the presence of SARS-CoV-2 from nose swabs done on patients. I added an extra drop for good measure, and there was not enough liquid left for a second test when I was done. endobj Discover the fast, proven, and trusted COVID-19 antigen card test that is readily available over-the-counter at retailers across the country. they don't detect the virus with as much sensitivity as PCR tests, BinaxNOW self-administered antigen test kit, CVS allows four tests per customer in stores. I got a couple PCR tests last year when I wanted to be sure I was healthy after coming home from college to visit my family, for instance. WebThe BinaxNOW COVID Ag Card is a point of care, rapid antigen test that provides results in as little as 15 minutes. STEP THREE:Order boxes of BinaxNOW via the link on this page. MV)s"y.$I3jm$PL%t M>W)2j'qlw$)1 $L;@8ndG| &=sO*&d}+ XeFc[')ax=j i0sUrr`ErELrQ47npe%"#A-`@6.wL*Mu( {3? -k=7Z69?YeuHOHg!. Abbott has decades of experience working in partnership with governments and in countries including in other pandemics where the need is most critical to improve public health. But given that I'm fully vaccinated and haven't come into contact with any sick people to my knowledge, I feel good about my result. All Rights Reserved. ***If your request is for greater than 2,500 COVID-19 test kits STOP Do not continue or complete this form, you will need to submit your request via the State of Texas Assistance Request (STAR) system by contacting your city or countys Office of Emergency Management.

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binaxnow reagent bottle